Health Tests · Labcorp OnDemand
Comprehensive Heart Health Test, $329
$329 · no doctor visit needed
- Order online, walk into 2,000+ locations — no appointment
- Physician order included — no doctor visit required
- Results in your portal in days
Same certified lab your doctor uses. HSA/FSA accepted.
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Order online for $329, fast 12–14 hours, then walk into any of 2,000+ locations — no doctor's visit needed. Seven advanced markers in one draw — particle counts, two inflammation lenses, and a diabetes risk score — with results in 3–6 days, and the honest limits on what they can tell you.
The short version
$329, one walk-in visit, results in 3–6 days
The Comprehensive Heart Health Test ($329) is the widest heart-health panel you can order without a doctor: an NMR LipoProfile with a particle count, Lp(a), ApoB, two inflammation markers, and a Diabetes Risk Index score — seven angles on heart and metabolic risk from a single blood draw. Order online, fast 12–14 hours, walk in for the draw, results in 3–6 days. It is a risk screen, not a diagnosis: it says which markers sit high or normal, not whether you have heart disease or diabetes.
Shopping links on this page go directly to Labcorp OnDemand. We don't earn a commission on orders.
Price
| Test | Price | |
|---|---|---|
| Comprehensive Heart Health Test | $329 | Order now → |
Prices checked Nov 11, 2026. HSA/FSA eligible. Self-pay; insurance not billed.
What the panel measures — seven angles on heart risk
One blood draw, seven angles. The NMR LipoProfile counts the number of LDL particles (LDL-P) circulating in your blood using nuclear magnetic resonance technology, and it includes a standard lipid panel (total cholesterol, calculated LDL, HDL, triglycerides) plus an insulin resistance score — the particle count is the upgrade over a standard cholesterol test, which measures how much cholesterol the particles hold rather than how many particles there are. Lp(a) measures lipoprotein(a), a type of “bad” cholesterol associated with increased risk of heart disease and other cardiovascular conditions; its levels are often genetically determined and high levels run in families. ApoB is the major protein on LDL particles — one molecule per cholesterol-carrying particle — so it counts the particles themselves. Lp-PLA2 measures an enzyme that marks active inflammation in your arteries or blood vessels; an elevated level may indicate a higher risk of developing heart disease and stroke. GlycA is a biomarker of systemic inflammation and cardiometabolic risk, measuring glycosylated acute-phase proteins; elevated levels have been associated with a higher risk of cardiovascular disease and diabetes. The Diabetes Risk Index (DRI) is a score for insulin resistance that analyzes specific lipids and certain amino acids linked to insulin resistance — it can flag diabetes risk even when blood sugar looks normal. And hs-CRP measures C-reactive protein at high sensitivity: a substance made by the liver in response to inflammation that rises quickly with acute inflammation. The test is not intended to diagnose cardiovascular disease, type 2 diabetes, or other diseases — it measures risk markers, and the numbers need a clinician to read them against the rest of your health.
Who should consider it — and who should skip it
This panel fits adults who want the most complete assessment of cardiovascular risk in one visit: people with an existing cardiometabolic condition such as diabetes, prediabetes, or elevated lipid levels; people with an existing inflammatory condition such as rheumatoid arthritis or inflammatory bowel disease; people concerned their age puts them at increased risk; people with a family history of heart disease, hypertension, or diabetes; and people who smoke, have obesity, or live a sedentary lifestyle and want to identify preventive measures. It is the wrong purchase if you already have diagnosed heart disease or diabetes: then your testing should run through your clinician, who can order the right markers and read them against your history. And if your standard lipid panel is already normal, you have no family history, and no other risk factors, it is a low-yield purchase — seven advanced markers earn their keep when there is a reason to look past the cholesterol number, not as a general wellness sweep. The narrower complete panel or a single marker test is the cheaper question in that case.
Reading the results: seven numbers, seven stories — and their honest limits
Your report prints each marker against the lab’s own reference range — read the numbers there, not against figures from the internet. The direction is what matters: higher LDL-P, ApoB, or Lp(a) generally indicate higher cardiovascular risk; an elevated Lp-PLA2 points to active inflammation in the arteries; an elevated GlycA points to systemic, chronic inflammation while hs-CRP catches the fast, acute signal; a higher DRI score indicates a higher risk of developing type 2 diabetes, and it can flag that risk even when blood sugar looks normal. The honest limits: these are probabilities, not verdicts. No single marker says you have heart disease or diabetes, none says when anything will happen, and no panel can separate the causes — genetics, diet, weight, insulin resistance, thyroid function, and smoking all push the numbers around. A high result anywhere in the panel is a prompt to talk to a clinician about the full picture — blood pressure, blood sugar, smoking, and family history — not a reason to order a supplement or overhaul your diet from one report.
An elevated marker means your result sits above the reference range, which is associated with higher risk — it does not diagnose heart disease or diabetes. Abnormal results deserve follow-up with your healthcare provider, who reads them against your history and decides what, if anything, changes.
Lp(a): the marker largely set by your genes
Most cholesterol numbers move with diet, weight, and medication. Lp(a) mostly does not: its levels are often genetically determined, and high levels run in families. That makes it a different kind of result from the rest of the panel. A high Lp(a) is not something you fix with a month of better eating — it is a lifelong risk factor to know about, so your clinician can weigh everything else around it. It is also the marker most people have never been tested for: a standard lipid panel does not measure it at all, which is why it is one of the four additions this panel makes over the narrower complete panel. If a parent or sibling had early heart disease and nobody in the family has ever had an Lp(a) measured, that is the clearest reason to pick this panel over the narrower one.
How walk-in heart-health testing works
You order the test online, then visit a patient service center for a standard venous blood draw — no doctor’s order, no appointment, and no insurance needed. The one prep rule that matters: fast for 12–14 hours before the sample collection (no food or drink, except water). Results typically post to a secure portal 3–6 days after your sample arrives at the lab. HSA/FSA accepted. Testing is performed in a CLIA-certified clinical laboratory. The test must be taken by the purchaser, and it is available to adults 18 to 100. A 20% off promo code is currently running — check the product page for the current price before ordering.
Common questions
Do I need to fast before this test?
Yes. Fast for 12–14 hours before the blood draw — no food or drink except water. The fast is what makes the lipid, ApoB, and particle-count numbers comparable: a fed draw measures your last meal, not your baseline.
What is the NMR LipoProfile?
It is a test that counts the number of LDL particles (LDL-P) in your blood using nuclear magnetic resonance technology. It also includes a standard lipid panel — total cholesterol, calculated LDL cholesterol, HDL cholesterol, and triglycerides — plus an insulin resistance score, for a more detailed analysis of cardiovascular risk than cholesterol amounts alone.
What is Lp(a), and why does it matter?
Lipoprotein(a) is a type of “bad” cholesterol associated with an increased risk of heart disease and other cardiovascular conditions. Its levels are often genetically determined, and high levels run in families — so it behaves differently from ordinary cholesterol, which moves with diet and weight. A standard lipid panel does not measure it.
What is Lp-PLA2?
Lp-PLA2 is an enzyme — lipoprotein-associated phospholipase A2 — that marks active inflammation in your arteries or blood vessels. An elevated level may indicate a higher risk of developing heart disease and stroke. It is the acute, artery-specific inflammation signal in this panel, where GlycA watches chronic systemic inflammation.
How is this different from the Complete Heart Health Test?
The Complete panel covers the lipid panel, ApoB, GlycA, and the Diabetes Risk Index. The Comprehensive panel adds four things: Lp(a), Lp-PLA2, hs-CRP, and the NMR LipoProfile particle count. Same single draw, same walk-in visit — a wider lens for a higher price. If you only want the core heart-health picture, the Complete panel is the cheaper question; if you want the particle count and the extra inflammation markers, this is the one.
Can this test diagnose heart disease or diabetes?
No. The test is not intended to diagnose cardiovascular disease, type 2 diabetes, or other diseases. It measures risk markers — elevated levels are associated with increased risk — and the results should be interpreted by a healthcare professional in the context of your overall health and other risk factors.
Is this a home test kit?
No. This is an in-person blood draw at a patient service center — you order online, then walk in for the sample collection. Your results arrive through a secure online portal, typically 3–6 days after your sample reaches the lab.
Ready to order?
Get the full heart-health picture this week
Order the Comprehensive Heart Health Test for $329 and walk in this week after a 12–14 hour fast — no doctor visit required.